What is the Grouchy gene?

The Grouchy gene is a genetic variant of gene 5-HTT which is designated 5-HTTLPR. 5-HTT provides with the instructions necessary to make the serotonin transporter. People with the grouchy version have lower transporter levels.

Genetically, 5-HTTLPR variation is due to size difference in the region of the gene. There are two variants a long form and a short form or the grouchy gene. Individuals with the short form make lower levels of less active transporters. 

The grouchy gene is also associated with increased risk for a variety of psychological conditions like depression, bipolar disorder, attention deficit disorder and Alzhiemer’s disease as well as with addictive behaviours and sudden infant death syndrome.

DNA Anxiety and Depression 5-HTTLPR Test

Find out whether you carry a genetic variant that disrupts your serotonin levels.

Web apps are available to users who have taken the test.

Get Test

Already took the test? Sign in to access your results.

Log In